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The original 1977 Monnier study showed that dialysate from sleeping rabbit brains (containing DSIP) could induce delta-wave sleep when infused into waking rabbits
Tirzepatide has emerging and strong cardiovascular data from the SUMMIT trial, which showed a 38% reduction in worsening heart failure events in patients with HFpEF and obesity
Taken together, evidence from neuroscience, human research, and clinical practice suggests meaningful overlap between obesity and addiction-related mechanisms. Lorenzo Leggio, MD, PhD, clinical director, National Institute on Drug Abuse, Bethesda, Md
Kakegawa T, et al
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