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Group comparison of demographic and clinical data were conducted using Welchs two sample t -test for continuous variables, except for age in which one-way ANOVA was used

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GLP-1 medications do not operate in isolationthey act on a complex metabolic network involving: Pancreatic insulin secretion Hepatic glucose output Gastric emptying Central appetite regulation Hormonal signaling Without baseline laboratory evaluation, cliniciansand increasingly, self-directed patientsrisk initiating therapy in a biological context they do not fully understand