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231 : 488493 Aureli T, Di Cocco M, Puccetti C, Ricciolini R, Scalibastri M, Miccheli A et al
Figure 1 Potential for differentiation with small molecules Detailed investigation of the small molecule GLP-1 receptor agonist danuglipron showed that, compared to natural GLP-1, the synthetic agonist showed differences in GPCR coupling to the cAMP and B-arrestin downstream biological pathways
These differences often come down to personal motivation and attitudes toward health
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Scientists discovered that people with type 2 diabetes have blunted incretin responses compared to people without diabetes
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