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Malabsorption (insufficient absorption of vitamin B12in the intestine) through, Insufficient production of intrinsic factor (a protein that is formed in the gastric mucosa and isrequiredfor the absorption of vitamin B12), Diseases in the terminal segment of the ileum (part of the small intestine), e.g

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In one study, mice treated with 20mg/kg of 5-amino-1mq three times daily for 11 days experienced a 5.1% reduction in body weight from baseline

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