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International Journal of Molecular Sciences, 19(7), 1987
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753,754 The expression of spermidine/spermidine N1-acetyltransferase 1 (SSAT1) is upregulated in the cortical penumbra of transient MCAO/R mice, and SSAT1 knockdown reduces cortical iron content, ROS production and 4-HNE levels, and alleviates I/R-induced cerebral infarction and nerve injury
So the protocol sets the dose to land GHK-Cu in a sensible daily range (~1.67 mg), and the three recovery/anti-inflammatory peptides ride along at their lower 0.33 mg each
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