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Skin around the eyes is significantly thinner than other facial areas, has minimal oil glands, and sits close to the sensitive eyeball
However, because the extracellular environment is highly conducive to oxidizing cysteine to cystine the ability to transport cysteine into cells is limiting
7 However, increasing lipophilicity is not a universal strategy as it may inhibit the biological activity of drugs of interest
Impaired glucagon suppression , resulting in inappropriate hepatic gluconeogenesis and elevated fasting glucose
Biochemical Pharmacology, 2024, DOI: 10.1016/j.bcp.2024.116565,
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