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Importantly, systemic semaglutide activates LC-NE neurons, and its acute appetite-suppressing effects are blunted when GLP-1Rs in the LC are blocked with local infusion of exendin-9 [91]
Limitations of Use Concomitant use of WEGOVY (semaglutide) tablets or WEGOVY (semaglutide) injection with other semaglutide-containing products or with any other GLP-1 receptor agonist is not recommended
They are different treatments with different risk profiles
They are not statements about human outcomes
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