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Reasons to track liver enzymes while on GLP-1s: Rapid fat mobilization during weight loss can temporarily affect liver function Pre-existing fatty liver may improve, and testing confirms progress Dehydration from reduced appetite can concentrate liver enzymes Combining GLP-1s with other medications increases liver processing demands Some individuals experience transient enzyme elevations that resolve with time If you're already monitoring pancreatic enzymes like amylase and lipase on GLP-1 therapy, adding liver markers gives you a complete picture of how your body is responding

FDA may be more cautious with a novel receptor combination, and the unresolved TRIUMPH-3 MACE question could invite additional review time

It is not off-limits, but portions should be small and always accompanied by vegetables

Iran J Pharm Res: IJPR 18(3):1602 Razavi MS et al (2022) Recent developments of nanostructures for the ocular delivery of natural compounds

Others use it long-term for weight maintenance