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This assessment includes bloodwork such as a lipid panel, glucose, and HbA1c, body composition measurement via DEXA when available, blood pressure, and a functional fitness test

Anecdotal reports of improved libido or mood lack objective hormone measurements and control groups

While these are different trials with different designs and not a direct head-to-head comparison, the data suggests retatrutide may deliver greater weight loss

AstraZeneca and EMD Serono have also reached deals with the administration in recent weeks.

They're usually injected and come with high price tags (up to $1,000/month) and a long list of potential side effects, from nausea and bloating to more serious risks like pancreatitis, bone-density loss, and even tumors