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[13] [14] Weight Loss and Metabolic Adaptation The concern about metabolic "damage" often stems from the well-documented phenomenon of adaptive thermogenesisthe body's natural reduction in energy expenditure that occurs with significant weight loss, regardless of the method used

Erythrocyte carbohydrate metabolism has been adapted to provide two additional pathways through which metabolic intermediates can be shunted or diverted as the need arises for the products of these shunts

Used primarily to treat high blood pressure (hypertension) and heart failure, it belongs to a class of drugs known as angiotensin-converting enzyme (ACE) inhibitors

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