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Users report visible changes in body composition within 3-4 weeks at working doses, with stubborn fat deposits in the lower abdomen and lower back responding noticeably

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Generally well tolerated in typical research-style protocols, with most reports noting mild or manageable effects when they occur

There is no conclusive evidence that semaglutide induced cancer development in tissue, which may imply that the development of cancer may pertain to other causes rather than semaglutide application [129]