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Current conditions being studied range from chronic kidney disease, sleep apnea, and nonalcoholic steatohepatitis to conditions not commonly associated with obesity like Alzheimer's, addiction, substance abuse, and smoking cessation
Most adverse events were mild to moderate and gastrointestinal in nature, resolving as dosing stabilised
This study also observed a decrease in circulating plasma GSH and 25(OH)VD 3 in HFD-fed mice
Saupe M, Rauschenberger L, Preu M, Oswald S, Fussek S, Zimmermann U et al
812 Diabetic kidney disease occurs in patients with T2DM as a consequence of reduced kidney function, triggered by hypertensive nephrosclerosis and unresolved acute renal failure as the main culminating reasons
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