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Using Ozempic specifically for weight loss without a diabetes diagnosis is an off-label use
The risk is highest during NAC infusions
Heidenreich PA, Bozkurt B, Aguilar D, Allen LA, Byun JJ, Colvin MM, et al
They have come into the limelight after a large double-blinded study published in NEJM, showed an average 14.9% decrease in weight in obese patients given semaglutide on top of lifestyle modifications, compared to 2.4% in the control arm (see research summary at end)
For those interested in diving deeper into the STRIDE trialincluding what triggered researchers' interest, the challenges they faced enrolling patients, and the broader implications of the studyour interview with lead investigator Dr
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