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That combination can be especially appealing to patients who want a structured path forward rather than trying to figure everything out on their own

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We can't jump from personal experiences to assuming that some biological process is not working when we don't yet even have a good idea of how that process would work in a healthy person yet

The evidence base is overwhelmingly preclinical, and there are no completed, published Phase 2 or 3 human efficacy trials only early-stage safety work [9]