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These mechanisms collectively accelerate lipid clearance, lower hepatic triglyceride content, and attenuate stellate-cell activation and oxidative stress
Novartis Found Symp
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Human GST A3-3, which, similar to the equine GST A3-3, shows the highest ketosteroid isomerase activity in mammals, has been subjected to analysis at the atomic level based on density functional theory calculations to put forward a refined mechanism for the isomerization of 5-AD (Dourado et al., 2014)
Coughlan KA, Valentine RJ, Ruderman NB, et al
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