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Many factors, such as increased uremic toxins in blood, hypertension, hyperhomocysteinemia, atrial fibrillation, endothelial dysfunction, impaired cerebral autoregulation, and accelerated arteriosclerosis are reported to have a direct impact on increased stroke risk underlying CKD 2,3
Receptor Dynamics and Sensitivity Prolonged exposure to any signaling molecule raises questions about receptor desensitization
Its always best to draw each dose immediately before administration
