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A review described DSIP as a still unresolved riddle, meaning its biology and clinical meaning remain unclear [8]
For aquacobalamin, the catalytic reaction is considered similar, releasing a water molecule instead of CN
Krajewski PK, Zotowska A, Szepietowski JC
As of mid-2026, neither compound is approved by the FDA or the EMA for any indication , so no established or approved human dose exists for either, and anything sold under those names outside a monitored trial is a research-use-only chemical of unverified identity
PMC 2694735
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