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Chen HM, Wei W, Smith D, Chan SC

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Active lignans isolated from schisandra, particularly schisandrin A, appeared to reverse P-glycoprotein-mediated multidrug resistance of various cancer cell lines to doxorubicin, vincristine, and paclitaxel (20)

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For example, in 2% albumin condition, the IC 50 is 5.39 when lipidation occurs at position 27, yet at position 26 it reaches 357

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