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In AD and PD, interventions aimed at suppressing ferroptosissuch as iron chelation, GSH replenishment, and GPX4 activationhave shown beneficial effects in preclinical models, including reduced oxidative stress, improved cognitive and motor functions, and delayed disease onset (409412)

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The combination of melatonin with vitamins C and E, demonstrated a more significant reduction in chlorpyrifos-ethyl (an organophosphate pesticide)-induced lung toxicity in mice (10)