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Our findings unexpectedly reveal that phosphorylation of just a small part of the Med14 protein plays a significant role in the response to GLP-1 drugsand in the metabolic response to hormones more broadly, says Reuben Shaw, PhD, a professor and holder of the William R

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We found that mitochondrial dysfunction induced by palmitoyl-L-carnitine leads to calcium overload and activation of kinases that contribute to tau hyperphosphorylation

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