however, some people using Ozempic have reported a side effect known as Ozempic face, characterized by a loss of facial fat that can lead to a more aged appearance
While estrogen and cortisol are not standard lab tests for patients taking GLP-1 medications (unless the patient has pre-existing conditions like PCOS or an adrenal disorder or is exhibiting specific symptoms), there is a growing body of research that indicates the drugs can affect and interact with these hormones, especially in certain patient populations, like women navigating menopause
Patients frequently describe a sensation of their internal battery being permanently stuck at one percent, alongside cognitive dysfunction, muscle weakness, and a persistent "brain fog" that makes concentrating nearly impossible
The anatomic position or time of onset is not related to sun exposure
Notably, approximately one-third of estrogen-regulated genes lack canonical EREs, suggesting alternative regulatory mechanisms (Johri et al., 2024