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Participants had an average starting BMI of 37 and average weight of 231 pounds

Side Effects and Safety Information The following safety overview draws from information published on the official Joi + Blokes website alongside general FDA context on GLP-1 receptor agonists

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An insulin syringe is preferred over a standard syringe because its fine markings allow for precise, small volume measurement, which matters when a single vial is being reconstituted to a specific concentration for research use

Tirzepatide is a dual GIP/GLP-1 receptor agonist prescribed for type 2 diabetes and weight management in the UK No causal link exists between Mounjaro and personality changes according to MHRA and EMA reviews Depression and anxiety are not listed as adverse reactions in the UK product information (SmPC) for tirzepatide Indirect psychological effects may occur related to weight loss, altered eating patterns, and metabolic changes Contact your GP promptly if you experience persistent low mood, significant anxiety, or concerning behavioural changes Hypoglycaemia when combined with insulin or sulfonylureas can cause mood changes requiring blood glucose monitoring Table of Contents Does Mounjaro Change Your Personality