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Helps in the synthesis and repair of DNA
Although the mechanisms linking GLP-1 receptor activation to blood pressure control require further investigation in humans, GLP-1RAs have been shown to lower blood pressure by augmenting natriuresis and diuresis, which are mainly mediated by their inhibition of the Na + /H + exchanger isoform 3, located at the brush border of the renal proximal tubule [23]
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The same study reported upregulation of MMP-9 transcription and activity following treatment with GSH (Bogani et al., 2007), and we observed a similar finding in GGC treated cells alone
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