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These results were described by lead investigators as the most significant weight loss outcomes reported in a clinical trial for type 2 diabetes at that time

Both support mitochondrial function through overlapping but distinct pathways: NMN/NAD+ provides the raw substrate for mitochondrial reactions MOTS-C improves the efficiency of how mitochondria use that substrate Together they're more effective than either alone for the mitochondrial decline that accelerates muscle loss after 50

The SUSTAIN-6 trial demonstrated that Ozempic significantly reduces the risk of major adverse cardiovascular events (MACE) in patients with type 2 diabetes and established cardiovascular disease

We should know the side effects that can be caused in the long term so that patients can be counseled on how to avoid long-term issues. Kipnis said he would like to see better long-term data as the next steps in this research