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YingHKimmelmanACLyssiotisCAHuaSChuGCFletcher-SananikoneEet al

Finally, GLP-1 itself acts reciprocally on the gut ecosystem by enhancing tight junction integrity, modulating bile acid metabolism, suppressing LPS-producing pathogens, and promoting colonization by beneficial taxa including Akkermansia muciniphila and Roseburia

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Its expression is regulated by circadian rhythms and BDNF in a manner consistent with homeostatic sleep regulation

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