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Based on hazard ratios, this equates to roughly a 58% increased risk of developing all thyroid cancers and a 78% increased risk of developing medullary thyroid cancer compared to controls

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Notably tirzepatide reduced the risk of developing type 2 diabetes by 94 percent and resulted in sustained weight loss over the three-year treatment period, Dr Jeff Emmick, PhD, Senior Vice President, Product Development, Eli Lilly remarked on the study findings at the time of the announcement

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Weight loss comparison at maximum doses Retatrutide produces the most weight loss at maximum dose, and the gap is meaningful