Am J Obestet Gynecol 140 , 412414
Research status FDA-approved for HIV lipodystrophy
Antioxidant enzymes/parameter SOD ( p = 0.0001, 0.0001, 0.0001), CAT ( p = 0.0001, 0.0001, 0.0001), GST ( p = 0.0001, 0.0001, 0.0001), and GSH ( p = 0.0001, 0.0001, 0.0001) were depleted, while TBARS levels increased significantly ( p = 0.0001, 0.0001, 0.0001)
Specifically, the 6,000-patient study found no increased risk for cardiovascular death, heart attack, stroke, unstable angina or heart failure in people with type 2 diabetes who had recently experienced acute coronary syndrome (ACS) events
Most constipation cases are manageable with dietary modifications, hydration, fiber supplementation, and over-the-counter remedies, though dose adjustment may be considered if symptoms persist despite appropriate management