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doi: 10.1038/s41573-025-01231-3

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We show that the heterogeneity in mitochondrial function and signalling observed across CRC samples could explain, and be used to predict, poor clinical responses in patients with locally advanced CRC

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Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity

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