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They concluded that these improvements were related to the acetyl L-carnitine (ALC)/ALA combinations ability to protect and repair age-induced mitochondrial DNA damage, thereby boosting mitochondrial function and improving energy turnover

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This opacity represents a significant limitation when evaluating potential effectiveness

It exists in virtually every cell, with the highest concentrations found in the liver (up to 10 mM), where it plays a central role in detoxification, and in the lungs, kidneys, and brain [2][3]