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The company has an internal once-weekly peptide (NNC-06620419, Phase 2 started October 2025), a ~$2B license on United Laboratories' UBT-251 (Phase 1b/2a running, 19.7% weight loss at 24 weeks in the Chinese Phase 2), a $2.2B collaboration with Septerna for small-molecule oral GPCR agonists including a triple, and a long-running in-house discovery pipeline
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However, clinical research exploring the therapeutic effect of metformin on OA at very limited
Other potential changes include alterations in cardiovascular risk factors
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