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Bain and Min remind us that GLP-1 receptor agonists reduce weight by promoting satiety, and that the additional weight reduction from the glucagon receptor agonism is likely to be due to effects on increasing energy expenditure

Launch of orforglipron will further reinforce this shift by drawing additional use away from older products, particularly among patients and clinicians seeking oral options over daily injectables that offer modest efficacy

Historically, thick sea ice blocked sunlight from reaching the shallow continental shelves of the Arctic for most of the year

GLP-1 medications like semaglutide or tirzepatide work by suppressing appetite, which can conflict with the calorie and nutrient demands of postpartum recovery

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