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The international journal of biochemistry & cell biology, 33(3), 205220
Overall, this phase 1b trial demonstrates that combined cagrilintide and semaglutide therapy is safe, well-tolerated, and offers clinically meaningful weight loss compared to placebo, warranting further investigation for weight management in obesity
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Injectable administration is hypothesized to provide systemic distribution, but human pharmacokinetic data for this route does not exist
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