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However, even if findings in one population cannot be generalised to a new setting if the association of interest is modified by patient characteristics, settings, or treatment variations which differ in the new setting, our findings are comparable to those observed in pharmacovigilance and pharmacoepidemiologic studies that do not find increased risk of SIS associated with GLP-1RA

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Engaging with GLP-1 users on platforms like TikTok and Instagram likely helps increase treatment awareness among younger adults, while also providing a positive example of what their own journey could look like

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Tissue distribution data suggest preferential accumulation in adipose depots, consistent with the mechanism-based selectivity investigators have come to expect

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