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The companies that manufacture the name-brand GLP-1s like Ozempic, Zepbound, and Wegovy havent meaningfully tested the drugs on people with BMIs lower than 27
Somm E, Montandon SA, Loizides-Mangold U, Gaia N, Lazarevic V, De Vito C, et al
In normal human physiology, GLP-1 and GIP are released by the gastrointestinal tract (enteroendocrine L cells in the small intestine and colon and enteroendocrine K cells respectively) in response to nutrient intake and have half-lives of 1 to 3 min [36]
GLP-1s help regulate glucose by: Increasing insulin secretion only when glucose levels are elevated (which lowers the risk of hypoglycemia) Slowing glucagon release (which prevents the liver from producing too much glucose) Slowing gastric emptying (which prevents sharp post-meal blood sugar spikes) Fasting, on the other hand, has been shown in some studies to naturally lower insulin levels and may help the body become more sensitive to insulin over time
How does it compare to alternatives specifically for lupus patients
