If you are gaining weight whilst taking retatrutide, it is understandably concerning but there are several plausible explanations that do not necessarily indicate treatment failure
Dosage protocols and practical use Evolv recommends starting with two tablets daily and adjusting up to three tablets daily as desired
Tips for managing stomach pain Eat smaller meals more frequently Avoid rich, greasy, or spicy foods Stay hydrated Avoid overeating Rest if symptoms worsen after meals Seek medical attention right away if you develop severe stomach pain with or without vomiting
# # # Disclosures: Rohit Loomba, MD, is a consultant or advisory board member for Aardvark Therapeutics, Altimmune, Anylam/Regeneron, Amgen, Arrowhead Pharmaceuticals, AstraZeneca, Bristol-Myer Squibb, CohBar, Eli Lilly, Galmed, Gilead, Glympse bio, Hightide, Inipharma, Intercept, Inventiva, Ionis, Janssen Inc., Madrigal, Metacrine, Inc., NGM Biopharmaceuticals, Novartis, Novo Nordisk, Merck, Pfizer, Sagimet, Theratechnologies, 89 bio, Terns Pharmaceuticals and Viking Therapeutics
Receptor binding and functional EC characterization in HEK293 cells expressing each of the three target receptors, including human and mouse orthologs