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ASK1 goes on to bind to TRAF2, which in turn activates downstream-signaling cascades, including the MKK3/4/6p38 and MKK4/7JNK signaling pathways 36,37 (Figure 4)
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This dynamic interplay enables the cell to regulate the ATP supply from the mitochondria according to its energy demands [71]
Nutritional factors also play a crucial role by providing the necessary substrates for anabolic processes and recovery mechanisms
Laursen, T., et al
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