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Detecting attenuation requires repeated measurements at the start of dosing and again after weeks of steady-state exposure, in the same individuals

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GLP-1 receptor agonistsincluding semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)are widely prescribed for type 2 diabetes and weight management

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We consider increasing after a couple weeks, if people need it, to half of the lowest dose

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