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& Sohal, R.S
Another study found that liraglutide decreased diabetic neuropathy-induced microglial cell activation in the cerebral cortex and thalamus of rats by reducing the expression of the NLR family pyrin domain containing 3 (NLRP3) protein in brain microglia [47]
Altogether, these results indicate that pharmacological inhibition of MAOB with KDS2010 effectively mitigates PTSD-associated deficits by reducing aberrant astrocytic GABA, restoring behavioral functions, and supporting the therapeutic potential of MAOB inhibitors in PTSD treatment
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