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In terms of glycemic control, these agents affect glucose metabolism through distinct pathways: GLP-1RAs enhance glycemic control by stimulating glucose-dependent insulin secretion, while SGLT2is lower blood glucose levels by inhibiting glucose reabsorption in the proximal renal tubules, leading to increased urinary glucose excretion
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In many cases, blood work provides valuable insights into why previous weight-loss efforts may have been unsuccessful
Image credits: Amy Sussman / Getty Image credits: Amy Sussman / Getty#11 John Goodman John Goodman's dramatic weight loss transformation raised questions about how he managed to do so.The onscreen star said he was his heaviest in 2011, weighing 400 lbs, but he managed to shed 200 lbs
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