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Their regulatory effect on myeloid cells, particularly macrophages, is critically important
If needed for a clear medical indication (such as treating pellagra in a pregnant patient), niacinamide can be used with caution, but unnecessary high-dose B supplementation is avoided in pregnancy
Breastfeeding is a season of nourishment, not pressure
Aging is another factor
This trial highlights the potential of combining agents with complementary mechanisms to tackle obesity more effectively than single-drug therapies
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