As mentioned earlier, given that GLP-1RAs have a regulatory impact on these immune cells, they could potentially serve as a therapeutic target for RA
See, e.g., FDA warning letter to Eurosirel S.P.A
1 2 3 4 Li Y, Perry T, Kindy MS, Harvey BK, Tweedie D, Holloway HW, Powers K, Shen H, Egan JM, Sambamurti K, Brossi A, Lahiri DK, Mattson MP, Hoffer BJ, Wang Y, Greig NH (January 2009)
Peptide 5 is shown in stick representation with carbon, nitrogen and oxygen atoms coloured purple, blue and red respectively
TRIUMPH-4 (obesity with knee osteoarthritis) reported positive results in late last year