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If you are someone who is impacted by MCAS you may want to consider discussing this study with your prescribing practitioner
Okay so the advice so far is kind of vague
There is no established contraindication to using NSAIDs with Wegovy , though these medications carry their own considerations: NSAIDs can cause gastrointestinal irritation, including stomach ulcers and bleeding, particularly with long-term use They should be used cautiously in patients with cardiovascular disease, kidney problems, or asthma Taking NSAIDs with food may reduce stomach irritation, though this may be challenging if Wegovy is causing nausea Avoid NSAIDs if experiencing vomiting or dehydration due to Wegovy, as this increases the risk of acute kidney injury Aspirin should not be given to children under 16 years except on specialist advice (due to Reye's syndrome risk) Non-pharmacological approaches: NICE guidance (NG193, NG59, NG226) emphasises the importance of non-drug approaches, particularly for chronic conditions
Psychopharmacology 236 , 603611 (2019)
Although the pathogenetic role of oxidative stress in these diseases is well established, there is still limited evidence on the therapeutic role of GSH in such conditions
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