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Andersen J, Urban N, Achimastou A, Ito A, Simic M, Ullom K, et al
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While mutagenesis studies clearly reveal that these residues within TM2 and ECL2 are important for both GLP-1 and oxyntomodulin function, alanine mutations in these regions generally had a larger impact on GLP-1 (Figures 4-5, Supplemental Figures 9-10)
All peptide therapy should be conducted under physician supervision with appropriate laboratory monitoring
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