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The medically appropriate rate is: 0.51% of total body weight per week For a 250-pound patient, that equals: 1.25 to 2.5 pounds weekly Faster loss increases risks of: Gallstones Lean muscle loss Hair thinning Hormonal disruption Safe loss preserves metabolism

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Things that can make sexual side effects more likely include: A history of low sex drive, erection problems, or painful sex

This anatomical abnormality is relatively common, particularly in individuals over 50 years of age and those with obesity