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Support multiple reputable generic/biosimilar manufacturers to avoid over-dependence on one supplier.[7] This would improve the reliability of manufacturing and distribution systems
A synthetic form of L-Ergothioneine, an antioxidant amino acid that brightens dullness, protects against pollution damage, and reduces signs of premature ageing, such as crows feet and fine lines
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Most clinical studies have examined these substances independently rather than in combination, so the safety profile and potential synergistic or additive effects remain inadequately characterised
Compounds used for in vivo experiments were further purified by size exclusion chromatography using a HiLoad Superdex 200 pg column (GE Healthcare) and further characterised for endotoxin level using the LAL Kinetic-QCL (Lonza) and integrity by LC/MS using an Acquity UPLC system coupled to a Synapt G1 mass spectrometer (Waters)
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