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1 Introduction In the past decade, obesity and related co-morbidities have become critical public health problems and serious medical conditions worldwide ( 2 )
Several DPP-4 inhibitors are renally excreted including alogliptin, sitagliptin, saxagliptin and vildagliptin (90)
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It increased cellular 'stemness' and activated multiple repair pathways simultaneouslysuggesting it works as a broad biological reset signal
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