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In this context, both the activation of the arc operon (linked to arginine fermentation) and the glycerol reductive pathway can be interpreted as parallel compensatory strategies to maintain redox balance and energy production in the double mutant

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Dehydration and insulinopenia are necessary and sufficient for euglycemic ketoacidosis in SGLT2 inhibitor-treated rats

Signal Transduct Target Ther 7(1):391