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USP22 protects against myocardial ischemia-reperfusion injury via the SIRT1-p53/SLC7A11-dependent inhibition of ferroptosis-induced cardiomyocyte death
Elevated cortisol promotes visceral fat storage, increases appetite for calorie-dense comfort foods, and disrupts sleep
Intentional appetite suppression can work against those goals
Keywords , weight loss , liver fibrosis , phase 3 clinical trial , metabolic syndrome , non-invasive tests 0 1 INTRODUCTION Metabolic dysfunction-associated steatotic liver disease (MASLD) has become a leading cause of chronic liver disease worldwide, tightly linked to obesity, type 2 diabetes mellitus (T2DM), and other components of the metabolic syndrome [1]
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