One consideration: The drug must be taken first thing in the morning, with no more than half a glass of water, and 30 minutes before any food
Summary SGLT2-i exert more consistent BP-lowering effects than GLP-1RA, largely due to their diuretic-like action
La introduccin de cambios en la cadena peptdica para reducir la degradacin por DPP-4, junto a la acilacin que facilita su unin no-covalente con la albmina, result en formulaciones de accin prolongada, posibilitando su aplicacin a la prctica clnica3,5
Why this matters: combination tablets can simplify a routine, but they also combine the cautions of both ingredients
Biological & Pharmaceutical Bulletin, 45 (8), 11911197