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This triple-agonist mechanism is what distinguishes retatrutide results from single or dual agonist peptides, as each receptor pathway contributes unique metabolic benefits

This action tells your body to: These combined effects help lower blood glucose levels and support weight loss, which is why GLP-1 receptor agonists are used to treat type 2 diabetes and obesity

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There is a real concern about sarcopenia for GLP-1RAs if you look at the small portion of participants who underwent DXA: IMG_59371284852 107 KB In this subset, total mass loss was ~14 kg